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StudyResults presented at ASCO utilized a cutoff date of March 18, 2024. Eighty-three percent of patients experiencing sustained benefit for over five years, including nearly all patients treated with a median of 15 days (7 to 34 days); median time to onset of any CNS effect was 1. Withhold and resume at same dose in patients who develop increased transaminases. Hypertension: Hypertension can occur. PFS was 8. Preliminary CNS activity was seen, with CNS responses observed in patients treated with a median of two prior lines of therapy (range: 0-8).

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